Ondansetron is a 5-HT3 receptor antagonist, directed for vomiting and nausea affected through radiation therapy, cancer chemotherapy, and surgery. It prevents serotonin receptors in the vomiting core and on nerves providing the digestive.
How to use Ondansetron?
It arrives as a tablet, a fast-dissolving tablet, an oral solution to take by mouth, and an injection applied intravenously. The initial dosage of this medicine is normally taken 30 minutes before the source of chemotherapy, 1 to 2 hours before the commencement of radiation therapy, or 1 hour before surgery. Further doses are sometimes taken one to three times a day throughout chemotherapy or radiation therapy and toward 1 to 2 days after the conclusion of treatment.
Dosage & when it is to be taken?
Oral: Prevention of post-op illness and vomiting- 16 mg 1 hour prior to anesthesia.
Nausea and vomiting connected with cancer chemotherapy- 24 mg as an individual dose 30 minutes prior to the commencement of regular chemotherapy. Less emetogenic chemotherapy and/or radiotherapy: 8 mg 2 hours prior to treatment accompanied through 8 mg 8-12 hours next.
While it is not to be taken (Contraindications)
The simultaneous application of apomorphine including ondansetron is contraindicated and identified hypersensitivity.
Why it is directed (Symptoms)?
This drug is a 5-HT3 receptor antagonist, directed for nausea and vomiting provoked with radiation therapy, cancer chemotherapy, and operation. It prevents serotonin receptors in the vomiting market and proceeding nerves providing the digestive method.
Warnings and Precautions?
It may change the heartbeat, and cause critical liver impairment. Caution is required while applied in cardiac disorders, patients who are on medicines that can increase QT, or patients with electrolyte irregularities, throughout pregnancy and breastfeeding. It may veil rising ileus and/or gastric distension.
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